For details on IUPAC characters usage see here
Is your sequence ready, or do you need to remove unwanted characters? To clean or not to clean?
Clean and Randomize Just Randomize
Select the number or randomization cycles
1 2 3 4 5 Number of randomization cycles
If the sequence needs cleaning, the selection of the correct alphabet is required
unambiguous DNA: GATC Protein Letters: ACDEFGHIKLMNPQRSTVWY unambiguous RNA, allowed: GAUC
ambiguous DNA, allowed: GATCRYWSMKHBVDN ambiguous RNA, allowed: GAUCRYWSMKHBVDN Protein Letters: ACDEFGHIKLMNPQRSTVWY Protein, Extended: ACDEFGHIKLMNPQRSTVWYBXZ
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Paste your DNA sequence below in any format. Max 50.000 characters allowed to limit server load